Email: landon.edgar (at) utoronto (dot) ca

Scientists

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Landon J. Edgar, Ph.D.
Principal Investigator

Assistant Professor,

The University of Toronto

Department of Pharmacology & Toxicology

Graduate Students

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Dzhangar earned his Pharm.D. degree at the University of Debrecen, Hungary. As an undergraduate, Dzhangar gained research experience in the Laboratory of Cellular and Molecular Physiology under the co-supervision of Dr. Attila Olah and Dr. Toth Fanni. The goal of this project was to study the influence of endocannabinoids on epidermal differentiation in the context of skin pathologies. This work identified the mtCB1 receptor as a key regulator of the mitochondrial ROS generation and highlighted its possible impact on epidermal cell differentiation. This project eventually shifted to the study of mitochondrial disorders as precursors to skin disease. Currently, Dzhangar is a Ph.D. student in The Edgar Lab and will focus on using synthetic carbohydrate chemistry to develop next-generation tools for editing specific glycans on the surface of immune cells.

Dzhangar Badmaev, Pharm.D.
Ph.D. Student (2021–Present)

Focus: Synthetic Chemistry, Glycobiology

Melissa is a fourth-year undergraduate student in the pharmacology specialist program at the University of Toronto. She is interested in studying the immune system in health and disease. Melissa will be completing her fourth-year research project in the Edgar Lab where her project will focus on expressing recombinant enzymes for the remodelling of glycans.

Melissa Wong
HBSc. Student (2018–Present)

Focus: Protein biochemistry

Eric is a second-year undergraduate student pursuing a pharmacology specialist and chemistry minor at the University of Toronto. His current interests are focused on learning about the roles of glycans in regulating immune responses and how these structures can be used to treat human diseases. Eric will be completing a second-year research experience in the Edgar lab focusing on the expression of recombinant enzymes for the remodeling of glycans.

Eric Chiu

HBSc. Student (2020–Present)

Focus: Protein biochemistry

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Aled is a second-year undergraduate research experience student in the Fundamental Genetics and its Applications Specialist program at the University of Toronto.  He is interested in exploring the role of the glycocalyx in immune function, and what applications glycan modification might have for enhanced therapies.  His current project in the Edgar Lab focuses on the chemical synthesis of metabolic inhibitors of eukaryotic glycosylation, for glycoengineering primary immune cells.

Aled Blundell

HBSc. Student (2020–Present)

Focus: Synthetic chemistry