Publications
Independent career
Izzati, F. N.*; Choksi, H.*; Giuliana, P.; Abd-Rabbo, D.; Elsaesser, H.; Blundell, A.; Affe, V.; Kannen, V.; Jame-Chenarboo, Z.; Schmidt, E. N.; Kuypers, M.; Avila, D. B.; Chiu, E. S. Y.; Badmaev, D.; Cui, H.; Matthews, J.; Mallevaey, T.; Macauley, M. S.; Brooks, D. G.; Edgar, L. J. (2025) Presentation of immunoregulatory sialoglycans on T cells is divergent between mice and humans. Cell Reports 44(7), 115933. (Independent work, published July 1st 2025; previously on bioRxiv: A Unified Atlas of T cell Glycophysiology). *Denotes equal contribution
Russo, E. E.; Rezayof, A.; Wallace, C.; Beerepoot, P.; Milenkovic, M.; Novalen, M.; Blundell, A.; Lipina, T.; Locke, J.; Christian, R.; Finnie, P. S. B.; Edgar, L. J.; Tyndale, R. F.; Watkins-Chow, D.; Ramsey, A. J.; Jones, S. R.; Salahpour, A. (2025) Characterization of a novel mouse model of Dopamine Transporter Deficiency Syndrome and pharmacological therapeutic strategies. bioRxiv (also in review). (Independent work, uploaded as a preprint March 25th 2025)
​​
Kannen, V.; Olafsen, N. E.; Das, S.; Giuliana, P.; Izzati, F. N.; Choksi, H.; Åhrling, S. S.; Cappello, P.; Teino, I.; Maimets, T.; Jaudzems, K.; Gulbinas, A.; Dambraukas, Z.; Edgar, L. J.; Grant, D. M.; Matthews, J. (2025) Loss of aryl hydrocarbon receptor reduces pancreatic tumour growth by increasing immune cell infiltration. Biochem. Pharmacol. 236, 116872. (Independent work, published March 14th 2025)
​
Kannen, V.; Rasmussen, M.; Das, S.; Giuliana, P.; Choksi, H.; Izzati, F. N.; Erlingsson, L. A. M.; Olafsen, N. E.; Cappello, P.; Teino, I.; Maimets, T.; Jaudzems, K.; Gulbinas, A.; Dambrauskas, Z.; Edgar, L. J.; Grant, D. M.; Matthews, J. (2025) Loss of PARP7 increases IFN-I signalling preventing pancreatic tumour growth by enhancing immune cell infiltration. Front. Immunol. 15. (published Jan. 9th 2025)​
​
Bodenstein, D. F., Powlowski, P., Zachos, K. A., El Sabbagh, D. E. S., Jeong, H., Attisano, L., Edgar, L. J., Wallace, D. C., Andreazza, A. C. (2023) Optimization of differential filtration based mitochondrial isolation for mitochondrial transplant to cerebral organoids. Stem Cell Res. Ther. 14, Article 202. (Published Aug. 15th 2023)
​
Edgar, L. J. (2021) Engineering the Sialome. ACS Chemical Biology. 16, 1829–1840. (Published Sept. 30th 2021)
Highlighted: Huang, M. L., Kiessling, L. L. (2021) Special issue on chemical glycobiology. ACS Chem. Biol. 16, 1793–1794.
Postdoctoral career
Edgar, L. J., Thompson, A. J., Vartabedian, V. F., Kikuchi, C., McBride, R., Woehl, J. L., Teijaro, J. R., Paulson, J. C. (2021) Sialic acid ligands of CD28 block co-stimulation of T cells. ACS Central Science. 7(9), 1508–1515. (Published Aug. 23rd 2021)
Woehl, J. L.*, Kitamura, S.*, Dillon, N., Han, Z., Edgar, L. J., Nizet, V., Wolan, D. W. (2020) An irreversible inhibitor to probe the role of Sreptococcus pyogenes cysteine protease SpeB in evasion of host complement defenses. ACS Chemical Biology. 15(8), 2060–2069. (Published July 14th 2020) *Denotes equal contribution.
Edgar, L. J., Kawasaki, N., Nycholat, C. M., Paulson, J. C. (2019) Targeted Delivery of Antigen to Activated CD169+ Macrophages Induces Bias for Expansion of CD8+ T cells. Cell Chemical Biology. 26, 131–136. (Published Nov. 1st 2018) Highlighted: Featured & a most read article (Nov. 2018)
Graduate career
Bassan, J., Willis, L. M., Vellanki, R. N., Nguyen, A., Edgar, L. J., Wouters, B. G., Nitz, M. (2019) TePhe: a phenylalanine analogue for monitoring protein synthesis with mass cytometry. Proceedings of the National Academy of Sciences of the United States of America. 116(17), 8155–8160. (Published April 10th 2019)
Edgar, L. J., Vellanki, R. N., McKee, T. D., Hedley, D., Wouters, B. G., Nitz, M. (2016) Isotopologous Organotellurium Probes Reveal Dynamic Hypoxia In Vivo with Cellular Resolution. Angewandte Chemie International Edition. 55, 13159–13163. (Published Sept. 22nd 2016)
Stewart, A. F., Williams, A. L., Lofgreen, J. E., Edgar, L. J., Hoch, L. B., Dicks, A. P. (2015) Chemistry Writing Instruction and Training: Implementing a Comprehensive Approach to Improving Student Communication Skills. Journal of Chemical Education. 93(1), 86–92. (Published Nov. 16th 2015)
Park, H., Edgar, L. J., Lumba, M. A., Willis L. W., Nitz, M. (2015) Organotellurium Scaffolds for Mass Cytometry Reagent Development. Organic and Biomolecular Chemistry. 13, 7027–7033. (Published June 4th 2015) Highlighted: “2015 Hot Article” Royal Society of Chemistry.
Edgar, L. J., Vellanki, R. N., Halupa, A., Hedley, D., Wouters, B. G., Nitz, M. (2014) Identification of Hypoxic Cells Using an Organotellurium Tag Compatible with Mass Cytometry. Angewandte Chemie International Edition. 53, 11473–11477. (Published Sept. 3rd 2014) Highlighted: Sensors and probes: A mass cytometry activity-based probe, Nature Methods, 2014, 11, 1092.
Edgar, L. J. G., Koroluk, K. J., Golmakani, M., Dicks, A. P. (2014) Green Chemistry Decision-Making in an Upper-Level Undergraduate Organic Laboratory. Journal of Chemical Education. 91, 1040–1043. (Published April 18th 2014) Featured on the front cover of The Journal of Chemical Education
Edgar, L. J. G., Dasgupta, S., and Nitz, M. (2012) Protecting-Group-Free Synthesis of Glycosyl 1-Phosphates. Organic Letters. 14 (16), 4226–4229. (Published July 30th 2012)